I’ve been working on a project where we had to use Flex on a .Net environment and it had to be realtime. I was a little worried at first that it could be tricky to set up. But with WebORB.Net it’s pretty easy. We used the integrated RTMP (Real Time Messaging Protocol) messaging server. It’s almost like using WCF. The most important differences are that, by default, objects are transmitted as Hashtable and calls can’t be synchronous.